Mounjaro (tirzepatide) may reduce the effectiveness of oral hormonal contraceptives because it delays gastric emptying and can affect medication absorption.
Why can Mounjaro affect birth control pills?
Tirzepatide slows stomach emptying. This may change how oral medications, including hormonal birth control pills, are absorbed.
When is additional contraception recommended?
Official prescribing information recommends switching to a non-oral contraceptive method or adding a barrier method for 4 weeks after starting treatment and 4 weeks after each dose increase.
Does it affect every contraceptive method?
Non-oral hormonal contraceptives are not expected to be affected in the same way. A healthcare professional can help select an appropriate method.
What if pregnancy is planned?
Patients should discuss pregnancy plans or a confirmed pregnancy with their healthcare professional. Tirzepatide should not be used for weight loss during pregnancy.
Conclusion
Mounjaro may reduce the effectiveness of oral hormonal birth control, especially after treatment initiation and dose increases. Additional or alternative contraception may be necessary.
Medical notice: Consult a healthcare professional before changing contraception.
